# Retraction Issued for Glioblastoma Study on AKT/mTOR and MDM2 Inhibition

The journal Nature has retracted a previously published study on glioblastoma multiforme, which claimed that combined inhibition of AKT/mTOR and MDM2 promoted cancer cell apoptosis and differentiation of cancer stem cells. The retraction indicates the findings are no longer considered reliable, affecting researchers who may have built upon this work.

**Importance:** 3/5

## Sources

### Science
- [Nature](https://www.nature.com/articles/s41598-026-66458-5) — 2026-08-12