# Christina Applegate Says She Was Misdiagnosed With MS: Back at Square One

Actress Christina Applegate revealed that she was misdiagnosed with multiple sclerosis and is now “back at square one,” calling the experience a “mindf—.” The disclosure highlights the uncertainty and emotional toll of diagnosing MS, while raising awareness of misdiagnosis in neurological conditions.

**Importance:** 2/5

## Sources

### Entertainment
- [Variety](https://variety.com/2026/tv/news/christina-applegate-misdiagnosed-ms-1236917323/) — Tue, 20 Oct 2026 11:53:21 +0000
- [BBC Entertainment](https://www.bbc.co.uk/news/articles/cqlyel3wnxmxo?at_medium=RSS&at_campaign=rss) — Tue, 20 Oct 2026 15:16:38 GMT

### World
- [The Guardian World](https://www.theguardian.com/tv-and-radio/2026/oct/20/christina-applegate-ms-misdiagnosed) — Tue, 20 Oct 2026 13:51:59 GMT

### Health
- [NPR Health](https://www.npr.org/2026/10/21/nx-s1-6009382/actor-christina-applegate-says-she-was-misdiagnosed-with-multiple-sclerosis) — Wed, 21 Oct 2026 04:42:30 -0400
- [BBC Health](https://www.bbc.co.uk/news/videos/cmewe41n5kdlo?at_medium=RSS&at_campaign=rss) — Wed, 21 Oct 2026 09:56:41 GMT