# Single-cell chromatin maps link regulatory variants to disease risk

New findings show that genetic variants shape chromatin accessibility in specific cell types, linking cell-type-specific gene regulation to disease. This helps explain how noncoding risk variants act and improves interpretation of disease genetics.

**Importance:** 3/5

## Sources

### Science
- [Nature](https://www.nature.com/articles/d41586-026-03067-2) — 2026-10-28
- [Nature](https://www.nature.com/articles/s41586-026-11173-4) — 2026-10-28