# New Tool Personalizes Sacubitril-Valsartan Use in Heart Failure

Researchers developed a phenomapping-based tool to identify which patients with heart failure with preserved ejection fraction are most likely to benefit from sacubitril-valsartan. The tool helps individualize treatment decisions, potentially improving outcomes and reducing unnecessary side effects.

**Importance:** 3/5

## Sources

### Science
- [Nature](https://www.nature.com/articles/s41746-026-03138-8) — 2026-08-12